Chinese scientist Han Jiankui, who no-one knew yesterday, excited the entire scientific and medical world by claiming that he had altered embryonic genes in seven different pairs during artificial insemination, thereby creating twins resistant to HIV. Recognized researchers around the world condemned their experiment of "designing a baby", which says it was about opening Pandora's box.
He worked as a deputy professor at the Southern University of Science and Technology in China, Shenzhen, claiming that he has used the CRISPR genealogy technology on embryos of seven different couples during the artificial insemination process, resulting in twins born this month.
The twins were born healthy a few weeks ago, and are known as Lulu and Nana. If he is right, these world's first children are born with changed genes. He says he has changed the twins embryonic in the hope that children will be resistant to HIV.
His claims are not confirmed by independent sources, and he secretly keeps information about the identity of the twin. However, he revealed this information to the AP news agency for a conference in Hong Kong, where he published the results of his work and hung up a video of his story on "Jutjub".
"I have the strong responsibility that this is not just the first, but an example. The company will decide what will be next – he said.
twins IMMUNE ON HIV
"Newspaper" reports that Chinese researchers published monthly medical documents on the Internet that reveal the details of this research, including the recruitment of couples on a voluntary basis. The result of all these efforts, he claims, is that immunized twins are born to HIV, thanks to CRISPR technology. He says his father had HIV, and his mother was not.
"The goal was to change the children's genes to protect them from future HIV infections," he told AP.
Although it is potentially an incredible medical achievement, there is great concern among the ethics of the process. As soon as he presented his work to the public, he immediately became a target of major controversy and repeated debate on "Designed Baby". The University distanceed from Hea and stated that he was interrupted and did not receive salary since February, and that an investigation is under way. He is not expected to return to work until January 2021, the University said in a statement, adding that he would immediately hire experts to investigate the matter.
AND AMERICAN SCIENTIST UNDER ISTRAGH
Meanwhile, another researcher is investigating that he is involved in altering genes of Chinese twins, according to ABC News. Rice University has launched a survey for a professor of biochemistry and genetic engineering, Dr. Michael Dim.
They said from the university that they did not know about their work and that this process was not done according to their knowledge in America, where genetic changes of human embryos are illegal. Smoke said he was in China when the participants agreed to make a genetic modification. He pointed out that they all understood the risks.
"Comparing reassignment with vaccines can be the way the legislators can describe it," he said.
PANDORA BOX IS OPEN
The research data have not yet been confirmed or published in a scientific journal, a standard protocol and more than 100 researchers, mostly from China, have condemned his publication as "madness" and unethical behavior. Researchers in an open letter say that the use of CRISPR-Cas9 technology to change human embryos is highly risky, unjustified and harmful to the reputation and development of biomedical society in China.
– Direct attempts on humans can only be described as galena. Pandora's box is open. We still have a glimpse of hope to close it before it's too late – say about 120 researchers in a letter on Chinese websites.
Yang Zhengang, professor of Fudan University, told Reuters that he signed the letter because change of genes is "very dangerous".
The Chinese National Health Commission earlier announced that it was "very worried" and ordered regional officials to immediately check and clarify this situation.
CRISPR is a molecular tool that allows researchers to modify DNA parts. Many researchers are interested in eliminating or curing genetic diseases. While the CRISPR-cas9 technique is used in adults, genetic changes in the embryos are another matter, as all changes can be transferred to their subsequent.
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