An international team of researchers discovered a new broad spectrum of antibiotics that contain arsenic that they want combat the emergence of antibiotic resistant bacteria, a problem that is already causing million deaths and that it can cause a health catastrophe in the future, according to the World Health Organization (WHO).
Barry P. Rosen, from the Herbert Wertheim School of Medicine, Florida International University (FIU), stated that the new antibiotic, named Arsinotricin (AST) is a "natural product produced by soil bacteria".
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Rosen, co-author of the study published in the journal Nature's Communication Biology, said in a statement that AST is "first and only known natural antibiotic" containing arsenic.
The study suggests that even though it contains this substance, researchers say the AST toxicity in human blood cells "It doesn't kill human cells in tissue culture."
"People get scared when they hear the word arsenic because it can be a poison and carcinogen, though the use of arsenic as antimicrobials and anticancer agents is well established"So Rosen.
According to the US Center for Disease Control and Prevention (CDC), some Two million people are infected each year in the country with drug-resistant bacteria, of which 23,000 die.
The World Health Organization (WHO) warned that "more and more infections, such as pneumonia, tuberculosis, gonorrhea and salmonellosis, will be more difficult to treat, as The antibiotics used to treat them become less effective".
"We run out of tools to fight these diseases. We need a powerful new antibiotic to solve this problem ", said Japanese Masafumi Yoshinaga, co-author of the report.
The researchers discovered itThe new antibiotic is "very effective" against some of the bacteria that affect public health the most, such as E. coli, which can cause diarrhea, gastroenteritis and other digestive disorders.
It also worked against Mycobacterium bovis, which causes tuberculosis in cattle, which could be used to treat this. human disease, even if they predict it New tests will be necessary.
The team hopes to work with the pharmaceutical industry to develop the compound in a drug, a process that can take ten years, although Rosen recalled that more than 90% of potential drugs "fail in clinical trials".
The study was conducted by researchers from the Department for Cell biology and Pharmacology of FIU and the Institute of Agro-Environmental Sciences (NARO), Japan.
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