For more than two decades, researchers from Scripps Research Center, in the United States they work with an ambitious goal in mind: creating one HIV vaccine. And even if the goal has not been achieved, there are progress that makes them think they are close to achieving it.
The latest is the development of a experimental vaccine which has had an excellent response in chimpanzees whose organism is very similar to that of humans. This vaccine injects special antibodies that neutralize a strain of HIV that most commonly infects people called Tier 2 Virus.
"We found that this type of neutralizing antibody, introduced into the body with a vaccine, can protect animals from viruses that look much like HIV present in the real world," said the doctor. Dennis Burton, Head of Center Immunology and Microbiology.
The discovery of these antibodies is in line with the work done by Scripp Research Center since 1990: identify the rare vulnerable areas that HIV has and help the immune system to create specific antibodies to attack in these areas.
"Because the HIV appearance is this, the first scientific evidence is that protection based on antibodies to the Tier 2 strain of HIV has been developed," says one of the authors of the study. "The question remainsHow can we achieve the same results in chimpanzees and other animals? "
At present, the vaccine will continue in an experimental phase with animals and its creators hope that they will soon be allowed to start test with people.
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